Indications
To improve and delay visible signs of ageing, including fine lines, loss of firmness, uneven skin tone and reduced radiance. Suitable for all skin types, including normal and dry skin.
A medical-grade formulation suitable for all skin types:
- Essential Renewal Serum – Retinoid potency 1: ideal for early signs of ageing, new to medical-grade retinoid users and sensitive skin
- Advanced Renewal Serum – Retinoid potency 2: ideal for skin acclimatised to medical-grade retinoids and those with more established signs of ageing.
Composition
RETINDUO® Technology: Combining retinol and retinal with a bioavailability booster, RETINDUO® accelerates cellular turnover to improve skin texture, refine pores and support the normalisation of sebum production.
EDAFENCE®: A patented technology which is clinically proven to protect the skin from pollution and other environmental stressors. This powerful antioxidant helps prevent free radical damage and blocks the cascade of damage and inflammation caused by pollution. It is also proven to prevent alterations to the skin barrier and reduce transepidermal water loss.
Niacinamide: A multi-functional active with antioxidant and anti-inflammatory properties, that supports and strengthens the skin barrier to improve resilience, while also helping to improve skin tone and enhance overall radiance.
Moisturising & Soothing Complex: A complex of soothing and hydrating ingredients, including bisabolol, glyceric acid, chamomile extract, vitamin C and vitamin E. This complex is designed to deliver intensive hydration, soothe the skin and provide antioxidant and anti-inflammatory benefits to protect and improve comfort during retinoid use.
Hyaluronic Acid: Helps attract and retain moisture to hydrate the skin, improving firmness and elasticity. Supports skin structure to enhance smoothness and resilience, while plumping the skin for a more youthful, dewy appearance.
How to use
Select a retinoid potency level based on skin sensitivity and previous use of medical-grade retinoids.
- Potency level 1: For sensitive skin and those new to medical-grade retinoids.
- Potency level 2: For skin acclimatised to medical-grade retinoids and as a step-up option after adjusting to and using potency level 1 daily. Step-up to potency level 2 should be done under the guidance of a skin clinic practitioner.
Apply in the evening to clean, dry skin, avoiding the eye area. Begin gradually and increase frequency as tolerated, following the ALLSKIN | MED Retinization Process and practitioner guidance to gradually achieve nightly use, typically over a 4–5-week period.
The best results are achieved when ALLSKIN | MED Renewal Serums are used as part of a holistic medical-grade protocol. This approach helps prepare the skin, optimise the skin barrier, and provide high levels of full-spectrum sun protection. Please refer to the ALLSKIN | MED Retinoid Renewal medical-grade protocol and follow your practitioner’s guidance.
Warnings
External use only. Avoid contact with eyes and mucous membranes. In case of contact with eyes and mucous membranes, rinse with plenty of water. Keep out of reach of children. Store at temperatures below 40ºC.
References
1 Compared to 0.5% Retinol in wrinkle amplitude and viscoelasticity. Instrumental Efficacy and Tolerance Assessment, 40 female subjects with normal to combination skin 35 -60 years of age, once-daily application for 84 days. Eurofins Product Testing, Cosmetics & Personal Care Spain, S.L.U., Spain (2025). Data on file.
2 Tolerance and Efficacy Assessment, 20 subjects with normal to combination skin (35-60 years of age}, application to face once daily for 27 days. Subjective Evaluation. CRO: AlYeDerm Clinic & Research, Spain, (2025). Data on file.
